Correlation of cognitive function and Sleep in adolescent depressive disorder patients with non-suicid-al self-injury behavior
Objective To analyze the association between cognitive function and sleep in adolescent depressive disorder patients with non-suicidal self-injury(NSSI)behavior.Methods A total of 100 patients with adolescent de-pressive disorder who attended our outpatient clinic from December 2021 to January 2023 were selected and divided into NSSI and non-NSSI groups based on the presence or absence of NSSI behaviors;the same scales and tests were evalu-ated to individuals in both groups,and general information was compared using the self-made clinical characteristics information table.The degree of depression was assessed using the Hamilton Depression Inventory(HAMD-17).Cog-nitive function was assessed by the Chinese Brief Neurocognitive Test(C-BCT).Sleep was assessed by the Pittsburgh Sleep Quality Index(PSQI).The differences in the scores of relevant scales and tests between the two groups were com-pared,and the correlation between cognitive function and sleep in the NSSI group was analyzed.Results The differ-ences in general information between the two groups were not statistically significant(P＞0.05).HAMD-17(P＜0.01)and PSQI scores(P＜0.05)were higher in the NSSI group than in the non-NSSI group,and C-BCT test score scores(P＜0.05)were lower in the NSSI group than in the non-NSSI group.Multiple linear regression analysis showed that daytime dysfunction had a significant effect on information processing speed(B=-1.081,P＜0.05).Sleep duration had a significant effect on attention(B=-4.099,P＜0.01),working memory(B=-2.472,P＜0.05),and comprehensive abilities with executive function(B=-3.103,P＜0.05).Sleep disturbance had a significant effect on working memory(B=-3.169,P＜0.05).And sleep quality had a significant effect on comprehensive abilities with executive func-tion(B=-8.604,P＜0.01).Binary Logistics regression analysis showed that lack of sleep is risk factor for attention(OR=11.572,P＜0.01).Decreased sleep efficiency is risk factor for working memory(OR=2.160,P＜0.05).Con-clusion Cognitive function and sleep status were more severely impaired in adolescents of depressive disorders with NSSI behaviors,and cognitive function was correlated with sleep status,with daytime dysfunction,sleep duration,sleep disturbance and sleep quality as influencing factors of cognitive function.
NETL
NSTL
万方数据
