目的 探讨在老年睡眠障碍治疗中,采用佐匹克隆与艾司唑仑的价值.方法 以2020年4月～2022年6月本院收治的80例睡眠障碍的老年患者,以序贯平衡法分组,一组接受艾司唑仑治疗(纳入对照组),一组接受佐匹克隆治疗(纳入观察组).对比两组临床疗效,并统计不良反应发生率,分析睡眠状态和精神状态.结果 观察组40例患者经佐匹克隆治疗后统计的临床疗效高于对照组(P＜0.05);观察组统计的不良反应发生率低于对照组(P＜0.05);观察组统计的睡眠状况自评量表(Self-Rating Scale of Sleep,SRSS)评分、焦虑自评量表(Self-Rating Anxiety Scale,SAS)评分、抑郁自评量表(Self-rating depression scale,SDS)评分低于对照组(P＜0.05);观察组简易精神状态量表(Mini-Mental State Examination,MMSE)评分高于对照组(P＜0.05).结论 在老年睡眠障碍治疗中采用佐匹克隆、艾司唑仑均可改善患者病情,但佐匹克隆治疗后安全性及有效性更高,同时可改善其睡眠质量,减轻疾病对患者身心状态的影响.
Clinical effect of Zopiclone and Estazolam in the treatment of elderly patients with sleep disorder
Objective To explore the value of zopiclone and esazolam in the treatment of senile sleep disorders.Methods In 80 elderly patients with sleep disorders admitted to our hospital from April 2020 to June 2022,one group received eszolam(included in the control group)and one group received zopiclone(included in the observation group).The clinical efficacy of the two groups was compared,the incidence of adverse reactions was counted,and the sleep state,psychological state and mental state of the two groups were analyzed.Results The clinical efficacy of the ob-servation group of 40 patients treated with zopiclone was higher than that of the control group(P＜0.05).The.incidence of adverse reactions in the observation group was lower than that in the control group(P＜0.05).The Self Rating Scale of Sleep(SRSS)score,Self Rating Anxiety Scale(SAS)score,and Self Rating Depression Scale(SDS)score in the observation group were lower than those in the control group(P＜0.05).The Mini Mental State Examination(MMSE)score in the observation group was higher than that in the control group(P＜0.05).Conclusion The use of zopiclone and esazolam in the treatment of senile patients with sleep disorders all can improve their sleep quality,but the safety and effectiveness of zopiclone treatment are better,and can improve their sleep quality and reduce the impact of the disease on the physical and mental state of patients.
ZopicloneEstazolamOld ageSleep disorderClinical effectsPsychological state
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