目的 探讨体外受精-胚胎移植(In-vitro fertilization and embryotr-ansfer,IVF-ET)反复种植失败患者出现创伤后应激障碍(Posttraumatic stress disorder,PTSD)的影响因素.方法 将我院2022年1月～2022年12月期间收治的75例IVF-ET反复种植失败患者作为研究对象,另选取同一时间段我院74例IVF-ET种植成功患者作为对照组,同时根据PTSD量表评分将IVF-ET反复种植失败患者分为非PTSD组(54例)和PTSD组(21例),观察比较研究组和对照组创伤后应激障碍及心理弹性情况;采用单因素及多因素Logistic回归分析IVF-ET反复种植失败患者PTSD的影响因素.结果 研究组PTSD评分较对照组高、而第1次实施IVF-ET前心理弹性量表(connor-davidson resilience scale,CD-RISC)评分较对照组低(P＜0.05);非PTSD组与PTSD组在职业、文化程度、居住地方面比较无显著差异(P＞0.05),在第1次实施IVF-ET前抑郁自评量表(Self-rating depression scale,SDS)评分、焦虑自评量表(Self-Rating Anxiety Scale,SAS)评分、CD-RISC 评分、内外向(intro verted and extroverted,E)量表评分方面比较存在显著差异(P＜0.05);多因素Logistic分析显示第1次实施IVF-ET前抑郁、焦虑、心理弹性差、性格内向是IVF-ET反复种植失败患者PTSD的独立影响因素(P＜0.05).结论 第1次实施IVF-ET前抑郁、焦虑、心理弹性差、性格内向是引起IVF-ET反复种植失败患者发生PTSD的相关影响因素.
Analysis of influencing factors of post-traumatic stress disorder in patients with repeated implantation failure of IVF-ET
Objective To explore the influencing factors of post traumatic stress disorder(PTSD)in patients with repeated implantation failures in in vitro fertilization and embryo transfer(IVF-ET).Methods 75 patients with recurrent implantation failure of IVF-ET admitted to our hospital from January 2022 to December 2022 were selected as the study subjects,and 74 patients with successful implantation of IVF-ET in our hospital during the same period were selected as the control group.At the same time,patients with recurrent implantation failure of IVF-ET were divided into non PTSD group(54 cases)and PTSD group(21 cases)according to the PTSD scale score,and the post-traumatic stress disorder and psychological resilience of the study group and control group were observed and compared;Single factor and multivariate logistic regression analysis was used to investigate the influencing factors of PTSD in patients with repeated implantation failure of IVF-ET.Results The PTSD scores of the study group were higher than that of the control group,and the scores on the Connor Davidson Resilience Scale(CD-RISC)before the first implementation of IVF-ET were lower than those of the control group(P＜0.05).There was no significant difference(P＞0.05)between the non PTSD group and the PTSD group in terms of occupation,education level,and place of residence before the first implementation of IVF-ET.There was a significant difference(P＜0.05)in the Self Rating Depression Scale(SDS)score,Self Rating Anxiety Scale(SAS)score,CD-RISC score,and introverted and extroverted(E)scale score.Multivariate logistic analysis showed that depression,anxiety,poor psychological resilience,and introversion were independent influencing factors for PTSD in patients with repeated IVF-ET implantation failure(P＜0.05).Conclu-sion Depression,anxiety,poor psychological resilience,and introversion before the first implementation of IVF-ET are relevant influencing factors for the occurrence of PTSD in patients with recurrent IVF-ET implantation failure.
In vitro fertilization embryo transferPost traumatic stress disorderPsychological resilienceDe-pressed
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NSTL
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