目的 分析综合康复训练联合药物治疗对精神分裂症患者不良情绪、依从性及生活质量的影响.方法 选择2019年2月～2022年2月于我院收治的精神分裂症患者90例,分为对照组(n=45)及观察组(n=45),对照组给予常规药物治疗,观察组给予综合康复训练联合药物治疗,比较两组患者疗效、依从性情况,分别于治疗前后行量表检查,比较两组患者治疗前后不良情绪[症状自评量表评分]及生活质量[自杀意念自评量表评分、生活质量评定问卷(Quality of life assessment questionnaire,GQOLI-74)]变化.结果 观察组、对照组患者治疗总有效率分别为86.67％、68.89％,观察组患者治疗总有效率明显高于对照组(P＜0.05).治疗后两组患者不良情绪明显改善,其中观察组患者不良情绪评分明显低于对照组(P＜0.05).观察组、对照组患者总依从率分别为91.11％、71.11％,观察组患者总依从率明显高于对照组(P＜0.05).治疗后两组患者生活质量明显改善,其中观察组患者躯体功能、心理功能、环境功能、物质功能等GQOLI-74量表组分明显高于对照组(P＜0.05).治疗后两组患者自杀意念明显改善,其中观察组患者绝望、睡眠、乐观、掩饰等自杀意念自评量表各因子分明显低于对照组(P＜0.05).结论 精神分裂症患者行综合康复训练联合药物治疗可有效缓解不良情绪、改善患者依从性,提高患者生活质量及治疗效果,可在临床推广应用.
The efficacy of comprehensive rehabilitation combined with pharmacotherapy on patients with schizophrenia
Objective To analyze the effects of comprehensive rehabilitation training combined with pharma-cotherapy on dysphoria,compliance and quality of life in patients with schizophrenia.Methods Ninety patients with schizophrenia admitted to our hospital from February 2022 to January 2023 were divided into a control group(n=45)and an observation group(n=45),and the control group was given conventional medication and the observation group was given comprehensive rehabilitation training combined with medication to compare the efficacy and compliance of the two groups.Changes in bad mood(SCL-90)and quality of life(Self-ratmg Idea of Suicide Scale and GQOLI-74)were compared.Results The total effective rate of treatment was 86.67％and 68.89％in the observation group and control group patients,respectively,and the total effective rate of treatment was significantly higher in the observation group than in the control group(P＜0.05).The bad mood of patients in both groups improved significantly after treatment,in which the bad mood of patients in the observation group was significantly lower than that in the control group(P＜0.05).The total compliance rates of patients in the observation group and control group were 91.11％and 71.11％,respec-tively,and the total compliance rate of patients in the observation group was significantly higher than that in the control group(P＜0.05).The quality of life of patients in the two groups improved significantly after treatment,in which the GQOLI-74 scale components of somatic function,psychological function,environmental function and material func-tion of patients in the observation group were significantly higher than those in the control group(P＜0.05).Suicidal ideation improved significantly in both groups after treatment,in which the components of the suicide ideation self-rat-ing scale such as despair,sleep,optimism,and masking were significantly lower in the observation group than in the control group(P＜0.05).Conclusion The combination of comprehensive rehabilitation training and pharmacotherapy for schizophrenia patients can effectively alleviate adverse emotions,improve patients'compliance,and enhance pa-tients'quality of life and treatment effects,and can be promoted in clinical practice.
Comprehensive rehabilitation trainingMedicationSchizophreniaDysphoriaAdherenceQuality of life
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