Correlation analysis between cognitive function and childhood trauma in children and adolescents with bipolar disorder
Objective To explore the relationship between cognitive function and childhood trauma in children and adolescents with bipolar disorder.Methods A total of 94 adolescents with bipolar disorder from January 2022 to July 2023 were selected as the observation group,and 90 healthy adolescents who volunteered to participate in the study during the same period were recruited as the control group.The Montreal Cognitive Assessment(MoCA)Scale was used to assess two groups of cognitive functions,including visuospatial and executive function,naming,attention,language,abstraction,delayed recall,and orientation.The childhood trauma questionnaire was used to evaluate two groups of childhood trauma,including emotional abuse,physical abuse,sexual abuse,emotional neglect and physical neglect.Pearson correlation coefficient was used to analyze the correlation between cognitive function and childhood trauma in adolescents with bipolar disorder.Results The total score and various scores of MoCA in the observation group were significantly lower than those in the control group(t=20.113,16.381,9.505,16.877,21.508,22.598,14.956,11.026,P＜0.05).The total score and various scores of childhood trauma in the observation group were significantly lower than those in the control group(t=5.752,4.561,5.670,3.428,7.412,3.054,P＜0.05).According to Pearson correlation coefficient analysis,the total score and various scores of MoCA in adolescent bipolar disorder were negatively correlated with the total score and various scores of childhood trauma(P＜0.05).Conclusion The cognitive function of adolescents with bipolar disorder is lower than normal level,and the childhood trauma is higher than normal level,and the cognitive function is negatively correlated with the childhood trauma.
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