The relationship between cerebral blood flow parameters and cognitive function in stroke patients with mild cognitive impairment
Objective To explore the relationship between cerebral blood flow parameters and cognitive function in stroke patients with mild cognitive impairment.Methods 45 stroke patients with mild cognitive impairment admitted to our hospital from January 2021 to September 2023 were selected as the combined group,and another 45 stroke pa-tients were selected as the non-combined group.Check and compare the cerebral blood flow perfusion parameters(frontal lobe,temporal lobe,parietal lobe,occipital lobe,thalamus,basal ganglia left and right)of two groups of patients using single photon emission computed tomography(Single Photon Emission Computed Tomography,SPECT).Ad-ditionally,evaluate their Montreal Cognitive Assessment Form(Montreal Cognitive Assessment,MoCA).Finally,analyze the correlation between cerebral blood flow perfusion parameters and MoCA scores in stroke patients with mild cognitive impairment using Spearman rank correlation analysis.Results The blood flow perfusion parameters of the right frontal lobe,left thalamus,and bilateral temporal,parietal,and occipital lobes in the combined group were lower than those in the non-combined group,with statistical significance(P＜0.05).The MoCA score of the combined group(23.56±2.12)was lower than that of the non-combined group(27.24±1.16),and the difference was statisti-cally significant(t=10.215,P=0.000).The right frontal lobe,bilateral temporal lobe,and left parietal lobe of stroke patients with mild cognitive impairment were positively correlated with MoCA score(P＜0.05,Bonferroni correction)Conclusion Patients with stroke combined with mild cognitive impairment have abnormal cerebral blood flow perfusion parameters,and the cerebral blood flow perfusion parameters in the right frontal lobe,bilateral temporal lobe,and left parietal lobe are positively correlated with cognitive function.Clinicians should closely monitor.
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