Correlation analysis between electroencephalogram gamma activity and cognitive function in patients with schizophrenia
Objective Analysis of eeg of gamma activity and cognitive function in patients with schizophrenia.Methods The clinical data of 100 patients with schizophrenia who were treated in our hospital from December 2020 to February 2023 were retrospectively analyzed,and they were set as the observation group.According to their EEG γ ac-tivity,they were divided into positive(n=79)and negative(n=21).Comparative observation,the control group cogni-tion[Trail Making Test(TMT),Symbol Coding(SC),and verbal memory(Hopkins Verbal learning test-revised)HVLT-R),Neuropsychological assessment batter(NAB),Brief Visuospatial Memory Test-Revised(BVMT-R),and Verbal fluency(Verbal)fluency,VF)],eeg gamma activity,The cognitive function and positive and negative syndrome scale(PANSS)scores of patients with positive and negative electroencephalogram(EEG)gamma activity in the observation group were compared.Spearman correlation coefficient was used to analyze the relationship between EEG gamma activity and cognitive function.Results Observation group BACS SC,HVLT-r,NAB,BVMT-R,VF scores were lower than the control group,eeg gamma activity positive proportion is higher than the control group(P＜0.05).Electroencephalogram(EEG)positive patients TMT,BACS SC,gamma activity HVLT-r,NAB,BVMT-R,VF scored lower than eeg gamma activity negative(P＜0.05).The scores of positive symptoms,nega-tive symptoms and general psychopathology of patients with positive EEG y activity were higher than those with nega-tive EEG γ activity(P＜0.05).Correlation analysis showed that eeg gamma activity,with BACS SC HVLT-r,NAB,BVMT-R,VF scores negatively correlated(P＜0.05).Conclusion Compared with healthy people,EEG gamma activity in patients with schizophrenia is significantly more,and the increase of EEG gamma activity is closely related to cognitive impairment.Clinical EEG examination results can be combined to further determine the severity of the patient's condition and formulate treatment plans.
NETL
NSTL
万方数据
