Protective factors of quality of life in inpatients with schizophrenia and bipolar disorder in Guangzhou
Objective To explore the protective factors of quality of life(QOL)in hospitalized patients with bipolar disorder or schizophrenia.Methods A total of 465 patients with bipolar disorder or schizophrenia who met the diagnostic criteria of the International Classification of Diseases(10th edition)(ICD-10)were continuously enrolled in four psychiatric inpatient departments in Guangzhou.The demographic and clinical characteristics of the patients were investigated and classified by self-designed questionnaire,the quality of life(QOL)was assessed with the World Health Organization Short Form for quality of life(WHOQOL-BREF),and the differences of QOL among different socio-demographic and clinical categories were analyzed,multivariate analysis of variance was used to analyze the protective factors of patients'quality of life.Results A total of 464 patients met the inclusion criteria.The scores of patients in four hospitals were 58.15±15.65 in physiological domain,49.13±8.20 in psychological domain,48.78±15.83 in social relationship domain and 51.48±14.44 in environmental domain,it was lower than Chinese norm stan-dard(P＜0.05).There were significant differences in sleep duration,exercise,age,physical chronic disease,sex,marital status,insight level,course of disease and smoking(P＜0.05).There was no significant difference in educa-tion,weight,age of onset and drinking(P＞0.05).The results of multivariate analysis of variance showed that male,having been married or cohabiting,high insight level,sleeping longer than 7 hours and regular exercise were the pro-tective factors of quality of life(P＜0.05).Gender*Insight Level,marital status*sleep duration*exercise status,marital status*Insight Level*sleep duration*exercise status,gender*marital status*Insight Level*exercise status had an interactive effect on patients'quality of life.Conclusion The QOL of hospitalized patients with schizophrenia and bipolar disorder is correlated with a variety of demographic and clinical characteristics,so targeted intervention should be carried out according to the relevant characteristics,so as to improve the QOL of patients and promote com-prehensive rehabilitation.
Quality of lifeSchizophreniaBipolar disorderSleepExercise
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