Objective To explore the protective factors of quality of life(QOL)in hospitalized patients with bipolar disorder or schizophrenia.Methods A total of 465 patients with bipolar disorder or schizophrenia who met the diagnostic criteria of the International Classification of Diseases(10th edition)(ICD-10)were continuously enrolled in four psychiatric inpatient departments in Guangzhou.The demographic and clinical characteristics of the patients were investigated and classified by self-designed questionnaire,the quality of life(QOL)was assessed with the World Health Organization Short Form for quality of life(WHOQOL-BREF),and the differences of QOL among different socio-demographic and clinical categories were analyzed,multivariate analysis of variance was used to analyze the protective factors of patients'quality of life.Results A total of 464 patients met the inclusion criteria.The scores of patients in four hospitals were 58.15±15.65 in physiological domain,49.13±8.20 in psychological domain,48.78±15.83 in social relationship domain and 51.48±14.44 in environmental domain,it was lower than Chinese norm stan-dard(P＜0.05).There were significant differences in sleep duration,exercise,age,physical chronic disease,sex,marital status,insight level,course of disease and smoking(P＜0.05).There was no significant difference in educa-tion,weight,age of onset and drinking(P＞0.05).The results of multivariate analysis of variance showed that male,having been married or cohabiting,high insight level,sleeping longer than 7 hours and regular exercise were the pro-tective factors of quality of life(P＜0.05).Gender*Insight Level,marital status*sleep duration*exercise status,marital status*Insight Level*sleep duration*exercise status,gender*marital status*Insight Level*exercise status had an interactive effect on patients'quality of life.Conclusion The QOL of hospitalized patients with schizophrenia and bipolar disorder is correlated with a variety of demographic and clinical characteristics,so targeted intervention should be carried out according to the relevant characteristics,so as to improve the QOL of patients and promote com-prehensive rehabilitation.
Quality of lifeSchizophreniaBipolar disorderSleepExercise
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