Analysis of the status quo,risk factors and cognitive function of metabolic syndrome with bipolar disorder
Objective To explore the comorbid metabolic syndrome(MS)in bipolar disorder rate and risk fac-tors,and the impact of MS on cognitive function.Methods From May 2020 to June 2023,106 cases of patients with bipolar disorder were selected as the study subjects.Patients comorbid MS were included into the observation group,while those without comorbid MS were included into the control group.The general information was compared between the two groups,and the risk factors for comorbid MS were analyzed.In the two groups,the MoCA scores were com-pared.Results Among the 106 patients with bipolar disorder,40 patients with MS,and rate was 37.74%.Between the observation group and the control group,there was of no statistically significant difference in terms including age,gender,smoking and drinking history,diagnostic typing,mood stabilizers,antipsychotic drugs(P＞0.05).In the observation group compared the control group,the rate of family history of diabetes and the type of medication was sig-nificantly higher(χ2=7.799,t=9.704,P＜0.05).Logistic regression analysis showed that family history of diabetes and type of medication were independent risk factors for comorbid MS of bipolar disorder.In the observation group,vi-sual space and executive function scores in the MOCA scale and total score was significantly lower compared with the control group(t=6.227,3.158,P＜0.05).Conclusion The comorbid MS in bipolar disorder rate is higher,and cognitive function is poorer;Family history of diabetes and type of medication are independent risk factors for comorbid-ity of bipolar disorder with MS.
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