目的 探究特发性中枢性性早熟(Idiopathic central precocious puberty,ICPP)患儿遵医行为的影响因素并观察照顾者的负性情绪.方法 选择2022年5月～2023年5月本院收治的100例ICPP患儿进行研究,依据遵医行为评分分为遵医行为良好组(63例)、遵医行为不良组(37例).比较患儿性别、年龄、骨龄、身高、体重、病程、用药时间、照顾者身份、照顾者学历、家庭关系、少儿心理健康量表(Children's mental Health Scale,MHS-CA)评分,进行单因素和多因素分析.以焦虑自评量表(Self-rating Anxiety Scale,SAS)、抑郁自评量表(Self-rating Depression Scale,SDS)评估照顾者的负性情绪.结果 与遵医行为良好组相比,遵医行为不良组照顾者非父母、照顾者不遵医嘱、不耐多药、治疗效果不佳、存在药物不良反应的比例较高,MHS-CA评分较低(P＜0.05);多因素Logistic回归性分析显示,照顾者非父母、照顾者不遵医嘱、不耐多药、治疗效果不佳、存在药物不良反应、MHS-CA评分较低是ICPP患儿遵医行为不良的影响因素(P＜0.05).遵医行为不良组患儿照顾者的SAS、SDS评分高于遵医行为良好组(P＜0.05).结论 ICPP患儿的遵医行为可能受到照顾者身份、照顾者遵医行为、是否耐多药治疗、治疗效果、药物不良反应及患儿心理健康等因素影响,另外遵医行为不良患儿的照顾者负性情绪更严重.
Influencing factors of compliance behavior in children with idiopathic central precocious puberty and negative emotion status of caregivers
Objective To explore the influencing factors of compliance behavior in children with idiopathic cen-tral precocious puberty(ICPP)and observe the negative emotions of caregivers.Methods A total of 100 ICPP children admitted to our hospital from May 2022 to May 2023 were selected for the study.They were divided into good compliance group(63 cases)and bad compliance group(37 cases)according to the score of compliance behavior.Gender,age,bone age,height,weight,course of disease,duration of medication,caregiver identity,caregiver education,fam-ily relationship and children's mental Health Scale(MHS-CA)score were compared,and univariate and multivariate analysis were performed.The negative emotions of caregivers were assessed by self-rating Anxiety Scale(SAS)and self-rating Depression Scale(SDS).Results Compared with the good compliance group,the proportion of non-parents,non-compliance,multi-drug resistance,poor treatment effect and adverse drug reactions in the poor compliance group was higher,and the score of MHS-CA was lower(P＜0.05).Multivariate Logistic regression analysis showed that non-parents,non-compliance,multi-drug resistance,poor treatment effect,adverse drug reactions and low MHS-CA score were the influencing factors of poor compliance behavior in ICPP children(P＜0.05).The scores of SAS and SDS in the poor compliance group were higher than those in the good compliance group(P＜0.05).Conclusion The compliance behavior of ICPP children may be affected by factors such as the identity of the caregiver,compliance behavior of the care-giver,multidrug resistance,treatment effect,adverse drug reactions and the mental health of the children.In addition,the negative emotions of the caregivers of the children with poor compliance behavior are more serious.
Idiopathic central precocious pubertyMedical compliance behaviorInfluencing factorsCare-giverNegative emotion
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