Effects of paroxetine on sleep and mood in patients with coronary heart disease complicated with insomnia
Objective To explore the value of Paroxetine in the treatment of coronary heart disease with in-somnia.Methods 200 patients with coronary heart disease and insomnia admitted to our hospital from March 2021 to March 2023 were recruited and divided into two groups by sequential balance method.The control group received psychological intervention(included in the control group),and the observation group received Paroxetine treatment(included in the observation group)on the basis of the first group.Compare the clinical efficacy of 200 patients and analyze the changes in their sleep quality and psychological state after intervention.Results The clinical efficacy of 100 patients in the observation group after Paroxetine treatment was higher than that in the control group(P＜0.05).The Self Rating Scale of Sleep(SRSS)score in the observation group was lower than that in the control group(P＜0.05).The Hamilton Depression Scale-17(HAMD-17)and Hamilton Anxiety Scale(HAMA)scores in the observation group were lower than those in the control group(P＜0.05).Conclusion The choice of Paroxetine in the treatment of coro-nary heart disease patients with insomnia can improve their sleep quality and psychological state,and improve the over-all treatment effect,which is worth learning and implementing.
ParoxetineCoronary heart diseaseInsomniaSleep qualityPsychological state
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