摘要
目的 分析缺血性脑卒中(IS)合并抑郁患者的MRI特征.方法 以2019年8月～2022年 12 月本院 94 例IS患者作为研究对象,将抑郁自评量表(SDS)≥53 分的 46 例作为研究组,SDS＜53分的48例作为对照组.比较两组的MRI特征.结果 研究组的额叶、颞叶、基底节区的缺血比例均显著高于对照组,差异均有统计学意义(P＜0.05);两组顶叶、枕叶、丘脑、内囊、海马体的缺血比例比较,差异均无统计学意义(P＞0.05).研究组额叶、颞叶、基底节区的表观扩散系数(ADC)值均高于对照组,差异均有统计学意义(P＜0.05).结论 IS合并抑郁患者的额叶、颞叶、基底节区的缺血比例显著较高,临床可根据MRI相关参数,防治本病.
Abstract
Objective To analyze MRI features in patients with ischemic stroke(IS)combined with depression.Methods Ninety-four cases of IS patients in our hospital from August 2019 to December 2022 were used as the study population.Forty-six cases with depression self-rating scale(SDS)≥53 were used as the study group,and 48 cases with SDS＜53 were used as the control group.MRI characteristics of the two groups were compared.Results The pro-portion of ischemia in the frontal,temporal,and basal ganglia regions was significantly higher in the study group than in the control group(P＜0.05).There were not statistically differences of ischemia in the parietal,occipital,thala-mus,internal capsule,and hippocampus between two groups(P＞0.05).The apparent diffusion coefficient(ADC)values in the frontal,temporal,and basal ganglia regions were higher in the study group than those in the control group(P＜0.05).Conclusion IS patients combined with depression have a significantly higher proportion of ischemias in the frontal,temporal,and basal ganglia regions,and the disease maybe can be prevented and treated clinically based on MRI-related parameters.
基金项目
河南省中医药科学研究专项课题(20-21ZY2112)
万方数据