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干眼患者焦虑、抑郁现状及其影响因素

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目的 观察并分析干眼患者焦虑、抑郁情况及其影响因素.方法 研究对象为2020年6月~2022年6月本院收治的干眼患者共90例,采用汉密尔顿焦虑量表(Hamilton anxiety rating scale,HAMA)和汉密尔顿抑郁量表(Hamilton depression rating scale,HAMD)评估患者的焦虑、抑郁情况并分组.比较两组的性别、年龄、病程、文化程度、年收入、睡眠时间、屈光状态、眼表疾病指数(Ocular surface disease index,OSDI)评分、泪液分泌试验(Schirmer'test,S'T)、泪膜破裂时间(Break-up Time,BUT)、角膜荧光素染色(Fluorescein staining,FL)等资料,进行单因素和多因素分析.结果 90例干眼患者中单纯焦虑患者11例、单纯抑郁患者8例、焦虑合并抑郁患者4例,共23例纳入焦虑抑郁组.焦虑抑郁组与非焦虑抑郁组的病程、年收入、睡眠时间、OSDI评分差异有统计学意义(P<0.05);两组性别、年龄、文化程度、屈光状态、SⅠT、BUT、FL比较差异无统计学意义(P>0.05);多因素Logistic回归性分析显示,病程>3年、年收入<5万、睡眠时间<6h、OSDI评分高是干眼患者焦虑、抑郁的影响因素.结论 干眼患者焦虑、抑郁发生率较高,可能与其病程、收入、睡眠不足、OSDI评分高等因素有关.
The status of anxiety and depression in patients with dry eye and its influencing factors
Objective The anxiety and depression of patients with dry eye and its influencing factors were ob-served and analyzed.Methods A total of 90 patients with dry eye admitted to our hospital from June 2020 to June 2022 were studied.Hamilton Anxiety Scale(Hamilton anxiety rating scale,HAMA)and Hamilton Depression Scale(Hamilton depression rating scale,HAMD)were used to assess the anxiety and depression of the patients and divided into groups.Gender,age,course of disease,education,annual income,sleep time,refractive status,ocular surface disease index(Ocular surface disease index,OSDI)score,tear secretion test(Schirmer'test,S'T),tear film rupture time(Break-up Time,BUT),corneal fluorescein staining(Fluorescein staining,FL)and other data of the two groups were compared for univariate and multivariate analysis.Results Among the 90 dry eye patients,11 patients with simple anxiety,8 patients with simple depression,and 4 patients with anxiety combined with depression were included in the anxiety and depression group.There were significant differences in disease course,annual income,sleep time and OSDI score between the anxiety and depression groups(P<0.05).There were no significant differences in gender,age,education level,refractive status,SⅠT,BUT and FL between the two groups(P>0.05).Multivariate Lo-gistic regression analysis showed that duration of disease>3 years,annual income<50,000 yuan,sleep time<6h,high OSDI score were the influencing factors of anxiety and depression in patients with dry eye.Conclusion The higher incidence of anxiety and depression in patients with dry eye may be related to the duration of disease,income,lack of sleep,and higher OSDI score.

Dry eyesAnxietyDepressionInfluencing factor

王玉琛、苏宇玉、杨军

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海口市第三人民医院眼耳鼻喉科(海口,571100)

海南省眼科医院眼科

干眼 焦虑 抑郁 影响因素

海南省卫生计生行业科研项目

19A200019

2024

国际精神病学杂志
中南大学

国际精神病学杂志

CSTPCD
影响因子:1.426
ISSN:1673-2952
年,卷(期):2024.51(5)