Analysis of the current status and risk factors of hospital-acquired pneumonia in patients with schizophrenia
Objective To explore the risk factors for hospital-acquired pneumonia(HAP)in inpatients with schizophrenia and provide reference for the formulation of clinical prevention and control strategies.Methods A total of 684 patients with schizophrenia in male and female psychiatric ward in 2021 were selected,including 21 patients in HAP group and 663 patients in non-HAP group.The general data of patients'age,smoking history,complicated underlying diseases,total course of disease,medication history and drug use were collected retrospectively.Univari-ate and multivariate regression analysis was used to explore the risk factors of HAP.Results 21 patients developed HAP.There were significant differences in age,underlying diseases,varieties of antischizophrenia and use of first-generation antipsychotics between the two groups.There was no significant difference in gender,urban and rural distri-bution,smoking history,total medical history,albumin,and fasting blood glucose between the two groups(P＞0.05).Multivariate Logistic regression analysis showed that age ≥ 65 years old,complicated with underlying diseases and use of more than two kinds of antipsychotics were independent risk factors for HAP in patients with schizophrenia.Conclusions Age ≥ 65 years old,complicated with underlying diseases and the use of more than two kinds of anti-psychotic drugs all increase the risk of HAP in patients with schizophrenia.Corresponding intervention measures can be adopted to reduce the incidence of infection.
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