Analysis of changes in cranial CT morphology in first-episode schizophrenia patients
Objective To explore the characteristics of cranial CT morphological changes in patients with first episode schizophrenia(FES).Methods Ninety-six FES patients from June 2021 to June 2023 were included.90 in-dividuals who underwent physical examinations during the same period were included in the cranial CT data,and were divided into the FES group and the normal group,respectively.The CT parameters of different brain structures and the occurrence of brain atrophy between two groups were compared.Results The Hasselblad value,bilateral frontal lon-gitudinal fissure distance,lateral fissure width,third ventricular width,and temporal lobe gyrus distance in the FES group were all higher than those in the normal group(P＜0.05).The anterior horn and ventricular index of the FES group were lower than those of the normal group(P＜0.05).The incidence of brain atrophy in the FES group was signif-icantly higher than that in the normal group,with mixed type,medullary type,and cortical type all significantly higher than those in the normal group(P＜0.05).Conclusion Compared with the normal population,FES has significant changes in brain CT morphology,such as increased distance between bilateral frontal slits,temporal lobe gyrus,and brain atrophy.When diagnosing and treating FES,attention should be paid to the changes in brain CT morphology.
First episode schizophreniaBrain CTMorphological ChangesCerebral atrophy
NETL
NSTL
万方数据
