The relationship between sleep spindle waves,serum total cholesterol levels,depression,anxiety,and cognitive function in first-episode elderly patients with depression
Objective To analyze the relationship between sleep patterns,serum total cholesterol(TC)levels,depression,anxiety,and cognitive function in first-episode elderly patients with depression.Methods Select 120 first-episode elderly patients with depression treated in our hospital from March 2022 to March 2024,the correlation of sleep spinning,serum TC level and Self-Rating Anxiety Scale(SAS),Self-rating Depression Scale(SDS)and Mini-mental State Examination(MMSE)were analyzed by Pearson.Results By Pearson analysis,there were significant associations between the number,amplitude,duration,density,TC,MMSE,SAS,and SDS scores in first-onset elderly depression patients(P＜0.05).Number was negatively correlated with amplitude,duration,SAS,and SDS score.Positive correlation with density,TC,and MMSE scores.Amplitude was positively correlated with duration,SAS,SDS score.Negative correlated with density,TC,and MMSE scores.Length was negatively correlated with den-sity,TC,and MMSE scores.Positive correlation with SAS and SDS score.Density was positively correlated with TC and MMSE scores.Negative correlated with SAS and SDS score.TC was negatively correlated with SAS and SDS score.Posi-tive correlation with the MMSE score.The SAS score was positively correlated with the SDS score.Negative correlated with MMSE score.The SDS score was negatively correlated with the MMSE score.The differences were all statistically significant(P＜0.05).Conclusion The sleep spindle waves and serum TC levels of first-episode elderly patients with depression are closely related to depression,anxiety,and cognitive function.
First onset elderly depressionSleep spinning wavesTotal cholesterolDepressionAnxietyCognitive function
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