The effect of modified non-convulsive electroconvulsive therapy in patients with refractory obsessive-compulsive disorder
Objective To investigate the curative effect of modified non-convulsive electroconvulsive therapy on refractory obsessive-compulsive disorder.Methods 80 patients with refractory obsessive-compulsive disorder who visited our hospital from May 2020 to May 2023 were divided into study group(n=40,modified non-convulsive elec-troconvulsive therapy combined with drug therapy)and control group(n=40,conventional drug therapy)according to random number table method.Yale-Brown Obsessive Compulsive Rating Scale(Y-BOCS),17-Hamilton Depression Scale(HAMD-17)and Hamilton Anxiety Scale(HAMA)were used to evaluate the clinical efficacy before treatment and at 2,4,8 and 12 weeks after treatment.The clinical efficacy was evaluated by the reduction rate.The side ef-fects scale(TESS)was used to evaluate the occurrence of adverse reactions during treatment.Results The scores of HAMA,HAMD-17 and Y-BOCS were lower than those before treatment(P＜0.05)at the end of 2nd,4th,8th and 12th week of treatment,and the scores of TESS in study group were lower than those in control group(P＜0.05).The total effective rate of the study group was significantly higher than that of the control group(P＜0.05).Conclusion Modified non-convulsive electroconvulsive therapy combined with routine drug therapy can significantly improve the therapeutic effect of refractory obsessive-compulsive disorder patients without increasing side effects.
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