首页|托莫西汀对ADHD患儿的疗效及对认知功能与执行能力的影响

托莫西汀对ADHD患儿的疗效及对认知功能与执行能力的影响

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目的 探讨托莫西汀治疗多动症患儿的疗效及对其认知加工与执行能力的影响.方法 本研究观察对象为2021年5月~2023年2月山东阳光融和医院收治的86例多动症患儿,均给予托莫西汀治疗,以自身治疗前后进行对比,采用整合视听持续测试评估临床疗效以及执行能力,采用Das-Naglieri认知测评系统评估认知加工能力.结果 治疗后多动症注意、对立违抗、多动与冲动、总得分均显著低于治疗前(P<0.05);治疗后注意、控制、综合注意、综合控制商数等执行能力评分均显著高于治疗前(P<0.05);治疗后Das-Naglieri系统继时加工、同时加工、注意、计划得分均显著高于治疗前(P<0.05).结论 托莫西汀治疗多动症不仅能降低对立违抗、多动、冲动等临床症状,还能提升其认知加工与执行能力.
Efficacy of tomoxetine in ADHD patients and its impact on their cognitive processing and execution abilities
Objective To explore the therapeutic effect of atomoxetine on patients with hyperactivity disorder and its impact on cognitive processing and execution abilities.Methods Eighty-six children with ADHD admitted to Shan-dong Sunshine Ronghe Hospital from May 2021 to February 2023 were selected as the study subjects.All patients were treated with Tomoxetine and compared before and after self treatment.The integrated audiovisual continuous testing were used to evaluate clinical effiicacy and execution ability.The Das Naglieri cognitive assessment system were used to assess cognitive processing ability.Results After treatment,attention,opposition defiance,hyperactivity and impulsivity,and total scores of ADHD were significantly lower than before treatment(P<0.05).The scores of attention,control,comprehensive attention,and comprehensive control quotient after treatment were significantly higher than those before treatment(P<0.05).After treatment,the scores of continuous processing,simultaneous processing,attention,and planning of the Das Naglieri system were significantly higher than before treatment(P<0.05).Conclusion Tomox-etine in the treatment of ADHD not only reduces clinical symptoms such as opposition,hyperactivity,and impulsivity,but also enhances its cognitive processing and execution abilities.

TomoxetineHyperactivity disorderCognitive processingExecution ability

周晓东、马静、王仁康、亓静静、赵秀秀

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阳光融和医院儿童保健科(潍坊,261000)

阳光融和医院儿科

托莫西汀 多动症 认知加工 执行能力

2024

国际精神病学杂志
中南大学

国际精神病学杂志

CSTPCD
影响因子:1.426
ISSN:1673-2952
年,卷(期):2024.51(6)