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右佐匹克隆治疗帕金森合并睡眠障碍的效果

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目的 探讨右佐匹克隆治疗帕金森合并睡眠障碍的疗效。方法 本研究选择2020年4月~2023年4月82例帕金森合并睡眠障碍患者,随机数字表法分为两组,对照组采用艾司唑仑治疗,观察组采用右佐匹克隆治疗。比较治疗前后匹兹堡睡眠质量指数量表(pittsburgh sleep quality index,PSQI)、失眠严重指数(Insomnia Severity Index,ISI)、帕金森病评定量表(unified Parkinson disease rating scale,UPDRS)。结果 两组治疗后PSQI指数、ISI指数均显著低于治疗前,观察组治疗后两项指数均显著低于对照组(P<0。05);两组治疗后UPDRS评分均显著降低,观察组治疗后评分显著低于对照组(P<0。05)。结论 右佐匹克隆治疗帕金森合并睡眠障碍能够有效提升睡眠质量,并能促进帕金森症状的缓解。
The effect of Dexzopiclone in the treatment of Parkinson's disease patients with sleep disorders
Objective To explore the therapeutic effect of right zopiclone in the treatment of Parkinson's disease with sleep disorders.Methods Eighty-two Parkinson's patients with sleep disorders from April 2020 to April 2023 were selected.They were randomly divided into two groups using the number table method.The control group was treated with estazolam,while the observation group was treated with dexzopiclone.The Pittsburgh Sleep Quality Index(PSQI),Insomnia Severity Index(ISI),and Unified Parkinson's Disease Rating Scale(UPDRS)before and after treatment were compared.Results After treatment,the PSQI index and ISI index of both groups were significantly lower than before treatment,while the observation group showed significantly lower levels of both indices after treatment than the control group(P<0.05).After treatment,the UPDRS score of both groups were significantly reduced,while the observation group had significantly lower scores than the control group(P<0.05).Conclusion The treatment of Parkinson's com-bined with sleep disorders with dexzopiclone can effectively improve sleep quality,and promote the relief of Parkinson's symptoms.

DexzopicloneParkinson's diseaseSleep disorders

李芳芳

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周口市中心医院神经内科二病区(周口,466000)

右佐匹克隆 帕金森 睡眠障碍

2024

国际精神病学杂志
中南大学

国际精神病学杂志

CSTPCD
影响因子:1.426
ISSN:1673-2952
年,卷(期):2024.51(6)