Effect of repetitive transcranial magnetic stimulation for post stroke cognitive impairment patients:a near-infrared spectroscopy study
Objective To investigate the effect of repetitive transcranial magnetic stimulation(rTMS)with functional near-infrared spectroscopy on post stroke cognitive impairment(PSCI)patients.Methods A total of 103 patients with PSCI in our hospital from October 2021 to October 2022 were enrolled,and divided into two groups by random number table methods.Routine group(n=50)received conventional treatment,while treatment group(n=53)received rTMS treatment.Montreal Cognitive Assessment(MoCA),near-infrared spectroscopy parameters,frontal lobe function and serological index were compared between the two groups.Results MoCA score presented no statisti-cal difference between the two groups at the baseline(P＞0.05),and the scores at post-treatment 2 and 4 weeks were(18.69±1.36)and(22.69±1.14)in treatment group,which were significantly higher than those in routine group(P＜0.05).The oxy-hemoglobin(oxy-Hb)level demonstrated no statistical difference between the two groups at the baseline(P＞0.05),and the levels at post-treatment 2 and 4 weeks were(0.29±0.04)mmol/L and(0.78±0.05)mmol/L in study group,which were significantly higher than those in routine group(P＜0.05).There was no signifi-cant difference in frontal function scores(P＞0.05).Patients in the treatment group had higher frontal function at 2 weeks(10.24±1.06)and 4 weeks(14.26±1.03)points than in the routine group(P＜0.05).The difference between EPCs and bF GF levels in the two groups before treatment was not significant(P＞0.05).In the treatment group,the EPCs(96.58±4.52)×106and bF GF(853.57±20.53)×106 were higher than those in the routine group(P＜0.05).Conclusion Repetitive transcranial magnetic stimulation(rTMS)can significantly improve the cognitive function and frontal lobe function of patients with post-stroke cognitive impairment,optimize the parameters of near-infrared spec-troscopy,thus promoting the rehabilitation.
Repetitive transcranial magnetic stimulationPost stroke cognitive impairmentNear-infrared spec-troscopyEffect
NETL
NSTL
万方数据
