目的 探讨脑外伤继发躁狂型精神障碍的危险因素.方法 选择2019年1月～2023年6月共85例脑外伤患者,观察受伤后3个月躁狂型精神障碍发生情况,并根据是否发生精神障碍划分为观察组与对照组,比较两组损伤部位、受伤原因等脑外伤特点以及年龄、性别等一般资料,纳入组间差异显著的资料进行多因素分析,探讨躁狂型精神障碍危险因素.结果 85例脑外伤患者22例(25.88％)发生了躁狂型精神障碍;观察组与对照组额叶损伤、颞叶损伤、弥漫性轴索损伤、低氧血症、颅内感染、入院格拉斯哥评分(GCS,Glasgow coma scale)、受伤后昏迷、年龄差异显著(P＜0.05),两组受伤原因、性别、受伤至入院时间差异无统计学意义(P＞0.05);多因素分析显示,额叶、颞叶、弥漫性轴索损伤、低氧血症是脑外伤继发躁狂型精神障碍的危险因素(P＜0.05).结论 脑外伤后容易继发躁狂型精神障碍,额叶、颞叶、弥漫性轴索损伤、缺氧等可能增加躁狂型精神障碍发生风险.
Analysis of Risk Factors for Bipolar Disorder Secondary to Traumatic Brain Injury
Objective To explore the risk factors for manic psychosis secondary to traumatic brain injury.Methods A total of 85 patients with traumatic brain injury from January 2019 to June 2023 were selected.Observe the occurrence of manic mental disorder 3 months after the injury,and were divided into an observation group and a control group according to the occurrence of mental disorder or not,comparing the characteristics of the traumatic brain injury such as injury site,cause of injury,and general information such as age and gender between the two groups,incorpo-rating the information of the significant differences between the groups for multifactorial analysis to explore the manic-type Psychiatric disorder risk factors.Results 22(25.88％)of 85 patients with traumatic brain injury developed manic psychotic disorder.The differences in frontal lobe injury,temporal lobe injury,diffuse axonal injury,hypox-emia,intracranial infection,admission Glasgow score(GCS,Glasgow coma scale),post-injury coma,and age were significant between the observation group and the control group(P＜0.05).There was no statistically significant differ-ence in the cause of injury,gender,and time from injury to admission between the two groups(P＞0.05)Multifactorial analysis showed that frontal lobe,temporal lobe,diffuse axonal injury,and hypoxemia were the risk factors for manic psychotic disorders secondary to traumatic brain injury(P＜0.05).Conclusion Traumatic brain injury is prone to secondary manic psychiatric disorders,and frontal lobe,temporal lobe,diffuse axonal injury,and hypoxia may in-crease the risk of manic psychiatric disorders.
Traumatic Brain InjuryManic Mental DisorderRisk FactorsSite of Injury
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