目的 探讨社区老年糖尿病患者慢性病共病状况及其与认知功能障碍的相关性。方法 数据来源于2018年中国健康与养老追踪调查(China Health and Retirement Longitudinal Study，CHARLS)数据，采用中文版简易精神状态检查量表(Mini-mental State Examination，MMSE)评估认知功能，采用二元Logistic回归探讨糖尿病老年人慢性病共病对认知障碍的影响。结果 共纳入803例糖尿病患者，认知障碍患病率为47。07％。Logistic回归分析显示，年龄增长(OR=1。601，95％CI:1。258～2。037)、糖尿病合并高血压(OR=0。623，95％CI:0。426～0。911)、血脂异常(OR=1。633，95％CI:1。104～2。414)、心脏病(OR=1。571，95％CI:1。006～2。454)、肾脏疾病(OR=2。003，95％CI:1。006～3。988)为认知障碍的危险因素。受教育水平越高(OR=0。775，95％CI:0。604～0。993)，有体力活动的习惯(OR=0。623，95％CI:0。426～0。911)为认知障碍的保护因素。结论 糖尿病患者合并其他慢性病与认知障碍风险增加相关。社区作为管理老年慢性病共病的主要场所，应加强预防、治疗这些共病，延缓认知能力的下降，提高居民健康水平。
Correlation analysis of chronic disease co-morbidities and cognitive dysfunction in community-dwelling elderly patients with diabetes mellitus
Objective To explore the chronic disease co-morbidity status and its correlation with cognitive dysfunction in community-based elderly diabetic patients.Methods Data were obtained from the 2018 China Health and Retirement Longitudinal Study(CHARLS)data,and cognitive function was measured using the Chinese version of the Mini-mental State Examination(MMSE).Binary logistic regression was used to explore the effects of chronic disease co-morbidities on cognitive impairment in older adults with diabetes mellitus.Results A total of 803 diabetic patients were included,and the prevalence of cognitive impairment was 47.07％.Logistic regression analysis showed that increasing age(OR=1.601,95％CI:1.258～2.037),diabetes mellitus combined with hypertension(OR=0.623,95％CI:0.426～0.911),dyslipidemia(OR=1.633 95％CI:1.104～2.414),heart disease(OR=1.571,95％CI:1.006～2.454),and kidney disease(OR=2.003,95％CI:1.006～3.988)were risk factors for cognitive impairment.Higher level of education(OR=0.775,95％CI:0.604～0.993)and habit of physical activity(OR=0.623,95％CI:0.426～0.911)were protective factors for cognitive impairment.Conclusion Comorbidity with other chronic diseases in diabetic patients is associated with an increased risk of cognitive impairment.The community,as a major site for managing chronic disease co-morbidities in the elderly,should be strengthened to prevent and treat these co-morbidi-ties,delay cognitive decline,and improve the health of the population.
Elderly patients with diabetesComorbidityCognitive dysfunction
NETL
NSTL
万方数据
