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焦虑抑郁对慢性非萎缩性胃炎消化道症状的影响

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目的 探讨焦虑抑郁对慢性非萎缩性胃炎(chronic atrophic gastritis,CAG)消化道症状的影响.方法 选择合肥市第八人民医院2020年2月~2023年4月90例CAG患者,评估焦虑/抑郁自评量表(self-ratinganxiety/depression scale,SAS/SDS)评分,并据此分为焦虑抑郁组以及无焦虑抑郁组.比较两组患者恶心、纳差、嗳气、腹胀、上腹痛等CAG临床症状评分以及红斑、出血、糜烂、胆汁反流等胃镜胃黏膜评分,分析SAS评分、SDS评分与CAG临床症状评分以及胃镜胃黏膜评分的相关性.结果 90例CAG患者检出焦虑或(和)抑郁共28例,检出率31.11%;焦虑抑郁组各项CAG临床症状评分及总分均显著高于无焦虑抑郁组,(P<0.05);焦虑抑郁组各项胃镜胃黏膜评分及总分均显著高于无焦虑抑郁组,(P<0.05);SAS评分、SDS评分均与CAG临床症状评分、胃镜胃黏膜评分呈正相关.结论 CAG患者焦虑抑郁等负性情绪检出率较高,且焦虑抑郁与CAG相关症状具有明显相关.
Effect of Anxiety and Depression on Gastrointestinal Symptoms in Chronic non-Atrophic Gastritis
Objective To explore the effect of anxiety and depression on gastrointestinal symptoms in Chronic Atrophic Gastritis(CAG).Methods Ninety CAG patients from the Eighth People's Hospital of Hefei City from Feb-ruary 2020 to April 2023 were selected as the study subjects.The self-rating anxiety/depression scale(SAS/SDS)were evaluated.According to this,they were divided into the anxiety depression group and the non-anxiety depression group.The CAG clinical symptom scores of nausea,anorexia,belching,bloating,and upper abdominal pain between two groups of patients,as well as the gastroscopy gastric mucosal scores of erythema,bleeding,erosion,and bile reflux were compared.The correlation between SAS score,SDS score,CAG clinical symptom score,and gastroscopy gastric mucosal score were analyzed.Results A total of 28 out of 90 CAG patients were diagnosed with anxiety or(and)de-pression,with a detection rate of 31.11%.The clinical symptom scores and total scores of CAG in the anxiety and de-pression group were significantly higher than those in the non-anxiety and depression group(P<0.05).The scores and total scores of various gastroscopy gastric mucosa in the anxiety and depression group were significantly higher than those in the non-anxiety and depression group(P<0.05).SAS score and SDS score are positively correlated with CAG clini-cal symptom score and gastroscopy gastric mucosal score.Conclusion The detection rate of negative emotions such as anxiety and depression were high in CAG patients,and there was a significant relationship between anxiety and depres-sion and CAG-related symptoms.

Anxiety and DepressionChronic non-Atrophic GastritisGastrointestinal SymptomsGastric Mu-cosal Symptoms

苏春娇、吴媛媛

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合肥市第八人民医院全科医学科(合肥,238000)

合肥市第八人民医院肾内科

焦虑抑郁 慢性非萎缩性胃炎 消化道症状 胃黏膜症状

2024

国际精神病学杂志
中南大学

国际精神病学杂志

CSTPCD
影响因子:1.426
ISSN:1673-2952
年,卷(期):2024.51(6)