Objective To investigate the detection of negative emotion in patients with gastroesophageal reflux and its influence on reflux symptoms.Methods Ninety-six patients with gastroesophageal reflux disease from April 2020 to April 2023 at Luzhong Hospital of Peking University Medical College were selected as the study subjects.The patient's Hamilton Depression Scale-17(HAMD-17)and Anxiety Scale(HAMA)were evaluated.They were set as the anxiety depression group and the non anxiety depression group.The general information of two groups of patients and the Gastro-esophageal reflux disease questionnaire(GerdQ)were compared.The upper/lower esophageal Sphincter resting pressure(UESP/LESP)of two groups of patients were measured.Results Ninety-six patients with gastroesophageal reflux disease were diagnosed with anxiety in 6 cases,depression in 5 cases,and anxiety combined with depression in 20 cases.There was a statistically significant difference in HAMD-17 Scale、HAMD-17 Scale,age,course of disease,and coexisting extraesophageal symptoms between the anxiety and depression group and the non-anxiety and depression group(P＜0.05).There was no statistically significant difference in gender and body mass index between the two groups(P＞0.05).The GerdQ score in the anxiety and depression group was significantly higher than those in the non-anxiety and depression group(P＜0.05),while the UESP and LESP were significantly lower than those of the non-anxiety and depression group(P＜0.05).The HAMD-17 score,HAMA score,and GerdQ score in the anxiety and depression group showed a posi-tive correlation,but a negative correlation with UESP and LESP(P＜0.05).Conclusion The detection rate of anxiety and depression in patients with gastroesophageal reflux disease is relatively high,and anxiety and depression were associ-ated with symptoms of gastroesophageal reflux disease and esophageal dynamic disorders.
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