首页|深圳市门诊患者和健康人群食源性寄生虫病血清学分析

深圳市门诊患者和健康人群食源性寄生虫病血清学分析

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目的 分析深圳市门诊患者和健康人群常见食源性寄生虫病的感染现状,为防治策略的制定提供科学依据. 方法 2013年1-12月,收集深圳市疾病预防控制中心寄生虫门诊就诊者的血清,同时按照整群随机抽样原则收集健康人的血清,采用酶联免疫吸附试验(enzyme-linked im-munosorbent assay,ELISA)检测华支睾吸虫、并殖吸虫、广州管圆线虫、猪囊尾蚴、棘球蚴和裂头蚴等6种常见食源性寄生虫的血清特异性抗体,通过描述性流行病学方法来分析人群血清学特征. 结果 收集门诊患者312人的血清,6种食源性寄生虫的总阳性率为24.35% (76/312),华支睾吸虫、并殖吸虫、广州管圆线虫、猪囊尾蚴、棘球蚴、裂头蚴血清抗体阳性率依次为12.01% (31/258)、6.98%(16/229)、6.19% (13/210)、8.75% (21/240)、5.37% (11/205)、9.20% (23/250).男性血清抗阳性率为27.33% (44/161)高于的女性的21.19% (32/151),性别间阳性率无统计学意义差异(x2=1.593,P>0.05);门诊患者中不同年龄组表现了不同的血清阳性率,最高血清阳性率的年龄组分布在21~50岁,高于20岁以下和50岁以上年龄组,但不同年龄组血清阳性率无统计学意义差异(x2=4.376,P>0.05);同时收集健康人群血清500人份,总阳性率为8.80% (44/500),华支睾吸虫、并殖吸虫、广州管圆线虫、猪囊尾蚴、棘球蚴、裂头蚴血清抗体阳性率依次为2.80% (14/500)、1.60% (8/500)、2.00% (10/500)、2.40% (12/500)、1.80% (9/500)、2.20% (11/500),男性血清阳性率9.67% (25/258)高于女性的7.85% (19/242),性别间阳性率无统计学意义差异(x2=0.526,P>0.05);健康人群中不同年龄组表现了不同的血清阳性率,最高血清阳性率的年龄组分布在21~50岁,高于20岁以下和50岁以上年龄组,不同年龄组居民血清阳性率有统计学意义差异(x2=8.625,P<0.05).深圳市门诊患者食源性寄生虫的阳性率高于健康人群的平均水平,差异具有统计学意义(x2=36.928,P<0.05). 结论 深圳市门诊患者食源性寄生虫血清阳性率高于健康人群感染的平均水平.食源性寄生虫病防治是深圳市寄生虫病防治工作的重点,应广泛宣传食源性寄生虫病防治知识,继续倡导健康饮食行为.
Serological analysis on food borne parasitic diseases of outpatients and healthy people in Shenzhen City
Objective To analyze the epidemic situation and trend of food-borne parasitic diseases in Shenzhen City thus to supply a scientific basis for developing the control strategies.Methods Serum samples of the outpatients at Shenzhen Centre for Disease Control and Prevention and healthy people were collected during January to December 2013.The specific antibodies of Clonorchis sinensis,Paragonimus,Angiostrongylus cantonensis,Cysticercus,hydatid and Sparganum in the samples were detected with ELISA.The characteristics of parasite infection was analyzed using descriptive epidemiological method.Results The total positive rate of food borne parasitic diseases was 24.35%(76/312).The rates of Clonorchis sinensis,Paragonimus,A ngiostrongylus cantonensis,Cystecercus,hydatid and Sparganum were 12.01%(31/258),6.98%(16/229),6.19%(13/210),8.75%(21/240),5.37%(11/205) and 9.20%(23/250) respectively in those 312 outpatients.The gender distribution of the total positive cases was 27.33% (44/161) in male and 21.19% (32/151) in female with no significant difference (x2=1.593,P>0.05).As to the age distribution of the total positive rates,the highest rate group was 21-50 years old group,however there was no significant difference between different age groups (x2=4.376,P>0.05).The total positive rate was 8.80 % (44/500) in 500 healthy people.The positive rates of above six parasites were 2.80% (14/500),1.60% (8/500),2.00% (10/500),2.40% (12/500),1.80%(9/500) and 2.20% (11/500) respectively.The total positive rate was 9.67% (25/258) in male,higher than that 7.85% (19/242) in female,however the difference was not significant (x2=0.526,P>0.05).As to the age distribution of the total positive rates,the highest rate was also in 21-50 years old group,while the difference between different age groups was significant (x2=8.625,P<0.05).Overall,the total positive rate in outpatients was significantly higher than that in healthy people (x2=36.928,P<0.05).Conclusion The infection rates of food borne parasitic infections in the outpatients is higher than that in healthy people in Shenzhen and the food-borne parasitic diseases were the major parasitic diseases to be prevented in Shenzhen areas and the healthy diet habit should be widely educated.

Food-borne parasitic diseasesSerum positive rateEnzyme-linked immunosorbent assay

黄达娜、张仁利、张泽娜、马艳秀、阳帆、吴春利、李玥

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518055深圳,深圳市疾病预防控制中心,深圳市科技创新委重大传染病监控重点实验室,深圳市病原微生物资源库建立与应用公共服务平台项目

421001衡阳,南华大学公共卫生学院

食源性寄生虫病 血清阳性率 酶联免疫吸附试验

2015

国际医学寄生虫病杂志
中华医学会,中国疾病预防控制中心寄生虫病预防控制所

国际医学寄生虫病杂志

CSTPCD
影响因子:0.463
ISSN:1673-4122
年,卷(期):2015.42(1)
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