Analysis of the characteristics and diagnostic values of ultrasonography for concurrent infection of Clonorchis sinensis in gallstone patients
Objective To analyze the ultrasonographic characteristics and investigate the clinical diagnostic value of ultrasonography for Clonorchis sinensis infection in gallstone patients.Methods From January 2009 to December 2012,886 gallstone patients were investigated retrospectively for the ultrasonographic characteristics,and the relationship between the ultrasonographic characteristics and the concurrent infection of C.sinensis was analyzed (diagnosed on the finding of eggs in bile).Results Of all the gallstone patients,the infection rate of C.sinensis was 43.3% (384/886).Contrast to this,the abdominal ultrasonography found additional sonograms from 33.6%(298/886) of the patients except the abnormal gallstones sonograms,and the difference was statistically significant (x2=26.455,P<0.05).And the overall sensitivity and specificity of ultrasonography for C.sinensis infection diagnosis was 43.0% (165/384) and 73.5% (369/502) respectively.Furthermore,the form of these additional sonograms,and its sensitivity and specificity was as follows:liver parenchyma enlargement and / or bile duct wall thickening(6.0%,99.6%),gallbladder wall thickening(≥ 3 mm) and / or gallbladder enlargement (10.4%,93.2%),cholecystitis (12.5%,91.8%),and biliary sludge,gallbladder sediments and / or sand-like stones (26.3%,85.1%).Conclusion For diagnosis of C.sinensis infection in gallstone patients,some ultrasonographic characteristics may display,however it is lack of clinical diagnostic sensitivity.