Apoptosis plays an important role in the growth and development of schistosome and other organisms.In recent years,some studies have been carried out on the observation of apoptosis phenomenon and investigation of apoptosis mechanism in schistosome,aiming at finding out new ways for prevention of schistosomiasis and new methods for control of this disease.A brief introduction in the research progress on the apoptosis phenomenon of schistosome and its host,and the identification of apoptosis related genes of schistosome,as well as the application prospect of the schistosome apoptosis studies was made in the review.