Research progress on molecular mechanism of severe malaria
Malaria caused by Plasmodium falciparum accounts for approximately one million deaths worldwide,most of whom are killed by severe malaria,particularly cerebral malaria (CM).Currently,it has been well studied on the clinical diagnosis,pathological analysis and therapy strategies,however,little is known of the pathogenesis of severe malaria including the occurrence,development,and involved molecular mechanisms.Here the research advances on the severe malaria-related key molecules,regulatory factors,and pathways were reviewed and discussed.
Severe malariavar gene familyPlasmodium falciparum erythrocyte membrane protein 1
NETL
NSTL
万方数据
维普
