The role of microRNA in pathogenic mechanism of schistosomiasis
MicroRNAs (miRNAs) are noncoding RNAs,21~25 nt in length,that widely exist in eukaryotic and a variety of virus.MiRNAs regulate the cell functions in the post-transcription level.MiRNAs widely participate in the cell growth,development,metabolism,apoptosis and other biological process of eukaryotic cells.Moreover,miRNAs are involved in the development of schistosome and its physiological metabolic process.In the early stage of schistosome infection,miRNAs play a vital role between schistosome and the host.In this review,the roles of miRNAs in the pathogenic mechanism of schistosomiasis were summarized.