HIV感染者弓形虫伴随感染的分子流行病学状况
Molecular epidemiology situation of the HIV patients accompanied with Toxoplasma gondii infection
安戈 1姚志军 2张海珠 2王东 2刘世国2
作者信息
- 1. 453003新乡,新乡医学院;450000郑州,郑州市疾病预防控制中心
- 2. 453003新乡,新乡医学院
- 折叠
摘要
弓形虫是一种重要的机会性致病原虫,是艾滋病患者常见的一种机会性感染寄生虫,其感染率占全部机会性感染的10％～30％.通常根据基因型的不同将弓形虫分为Ⅰ型、Ⅱ型和Ⅲ型,HIV感染者感染的弓形虫多为Ⅰ型,Ⅰ型弓形虫与其它类型弓形虫的致病性有很大差异,造成差异的根本原因是致病基因的不同,这些差异基因主要包括SAG1、SA G2、B1等.该文从弓形虫感染现状、伴随感染弓形虫的主要类型和各个类型之间的差异基因等方面,阐述HIV感染者弓形虫伴随感染的分子流行病学状况.
Abstract
Toxoplasma gondii is one of opportunistic pathogenic protozoan parasites.It is also one of the most common opportunistic infections in AIDS.The proportion of toxoplasmosis accounted for total opportunistic infection in HIV patients is 10％ to 30％.According to the differences of gene type,Toxoplasma gondii could be divided into type Ⅰ,type Ⅱ and type Ⅲ.HIV patients are mostly infected with type Ⅰ.There are great differences in pathogenicity between type Ⅰ and the other types which are caused by different genes.The different genes are SA G1,SA G2,B1 and so on.Based on the current situation of HIV patients accompanied with Toxoplasma gondii,the main type of Toxoplasma gondii in HIV patients and the different genes between the various types,we elaborated on the situation of the HIV patients accompanied with Toxoplasma gondii in molecular epidemiology in this paper.
关键词
弓形虫/HIV感染者/分子流行病学/差异基因Key words
Toxoplasma gondii/HIV patients/Molecular epidemiology/Different genes引用本文复制引用
出版年
2015
NETL
NSTL
维普
万方数据