记忆巩固研究的新进展
Recent progress on memory consolidation
吴燕琴 1柯鹏 1郑承捷 1郑静萱 1翁婧 1吴晓丹1
作者信息
- 1. 福建医科大学省立临床医学院,福建省立医院麻醉科,福州 350001
- 折叠
摘要
记忆包括记忆的编码、巩固和检索3个过程,其为大脑重要的高级神经功能之一.记忆巩固是指记忆的内部表征及其神经生物学随时间而变化的过程,其本质是在神经元、脑区或脑亚区之间形成新的稳定联系.记忆巩固在编码后立即开始,可能会持续若干天,甚至若干年.文章综述了记忆巩固在清醒和睡眠两种大脑状态的整个过程及记忆巩固神经加工机制等方面的研究进展,以期阐明记忆巩固现象的相关生物学机制.
Abstract
Memory includes three processes:memory encoding,consolidation and retrieval.It is one of the important higher neural functions of the brain.Memory consolidation refers to the process in which the internal characteristics of memory and its neurobiological basis change over time,and its essence is the formation of new stable associations between neurons,brain regions or brain subregions.Memory consolidation begins immediately after encoding and may last for days or even years.This paper summarizes the research progress on the whole process of memory consolidation in the wakefulness and sleep states and the neural processing mechanism of memory consolidation,in order to elucidate the biological mechanism of memory consolidation.
关键词
记忆巩固/海马体/突触可塑性/快速眼动睡眠/非快速眼动睡眠Key words
Memory consolidation/Hippocampus/Synaptic plasticity/Rapid eye movement sleep/Non-rapid eye movement sleep引用本文复制引用
出版年
2024
NETL
NSTL
万方数据