艾司氯胺酮在妇产科围手术期应用中的研究进展
Research progress on the perioperative application of esketamine in obstetric and gynecological patients
宋文学 1曹天彪1
作者信息
- 1. 酒泉市人民医院麻醉科,酒泉 735000
- 折叠
摘要
艾司氯胺酮与消旋氯胺酮有着相似的药理学特点,同时又克服了很多缺点,具有效能更高、可控性更强、副作用更少的优势,相信会逐步取代消旋氯胺酮制剂应用于临床.文章总结和概括目前国内外艾司氯胺酮在妇产科围手术期应用研究进展,综述该药物在妇产科椎管内麻醉、全麻,门诊短小手术、日间手术,以及术后镇痛、预防寒战、拮抗抑郁方面的相关研究进展,为艾司氯胺酮更加合理、安全地应用于临床提供参考,也为未来研究者提供和开拓新的思路及新的研究方向.
Abstract
Esketamine shares similar pharmacological characteristics with racemic ketamine.It also overcomes many weak-nesses,with higher efficacy,stronger controllability,and fewer side effects,and is expected to gradually replace racemic ketamine prep-arations in clinical applications.The article introduces the current research progress on the perioperative application of esketamine in obstetric and gynecologic patients at home and abroad,and summarizes the research progress of this drug on spinal anesthesia,general anesthesia,outpatient short surgeries,daytime surgeries,and postoperative analgesia,prevention of shivers,and antagonism against de-pression in obstetric and gynecologic patients.These findings will provide reference for the more reasonable and safe application of es-ketamine in clinical practice and facilitate and explore new ideas and research directions for future research.
关键词
艾司氯胺酮/妇产科学/围手术期Key words
Esketamine/Obstetrics and gynecology/Perioperative period引用本文复制引用
基金项目
酒泉市科技局民生项目(A类)(酒科发202170号)
出版年
2024
NETL
NSTL
万方数据