目的 基于文献计量学分析瑞马唑仑麻醉的研究概况、热点变化和发展趋势.方法 检索Web of Science核心合集数据库2010年1月至2023年6月瑞马唑仑的相关研究文献,应用文献计量学方法并借助信息分析软件VOS viewer对瑞马唑仑在麻醉研究中的发表年份分布、文献研究方法、研究人群分布、所属国家/地区分布、作者及机构分布、文献刊载来源分布、研究热点分析以及共被引期刊和文献进行共现和聚类分析,并绘制图谱.结果 检索到瑞马唑仑相关文献360篇,且在麻醉相关的研究中发文量逐年上升;研究类型以临床研究为主,研究人群中老年患者多于儿童患者;目前中国是发文量最多的国家,美国文献的被引频次居于前列;瑞马唑仑相关研究发文量≥5篇的作者17位、机构22个;刊文量≥10篇的期刊有8种;研究热点分析显示"咪达唑仑""丙泊酚""安全性""镇静""麻醉"为研究热点关键词;另外,有35篇文献共被引次数在20次及以上,其中共被引次数排名前10的文献有3篇来自Anesthesia and Analgesia.结论 瑞马唑仑在麻醉中作用的关注度逐年升高,目前的研究热点包括瑞马唑仑在胃肠镜检查、手术、全身麻醉以及重症监护治疗病房中的镇静疗效.瑞马唑仑有望成为临床上广泛应用的镇静药物.
Research progress on remazolam anesthesia:bibliometrics-based analysis
Objective To explore the research profile,topical changes,and trends in remimazolam anesthesia through bibliometrics-based analysis.Methods Retrieved the core database of Web of Science about remimazolam from January 2010 to June 2023,and analyzed the distribution of year of publication,methodology,population,country/region,authors and institutions,dis-tribution of publication sources,research hotspots,and co-cited journals and literature in anesthesia research through bibliometrics methods and the information analysis software VOS viewer for co-occurrence and clustering,and mapping.Results There were 360 articles related to remazolam,and the number of articles published in anesthesia-related research increased year by year.Clinical research is the main focus,and the number of elderly patients exceeds that of pediatric patients in the study population.China is cur-rently the country with the largest number of articles,while the United States is at the forefront of the citation frequency.There are 17 authors and 22 institutions with ≥5 publications on remazolam-related studies.There are 8 journals with 10 or more articles.Accord-ing to the analysis of research hotspots,"midazolam","propofol","safety","sedation"and"anesthesia"were the terms of research hot-spot.Furthermore,there were 35 articles with 20 or more total citations,with three of the top 10 co-citations from the journal Anesthe-sia and Analgesia.Conclusions The role of remazolam in anesthesia has drawn increasing attention year by year.The current re-search hotspots include the sedative efficacy of remazolam in gastro enteroscopy,surgery,general anesthesia,and intensive care units.Remazolam is expected to become a widely used sedative drug in clinical practice.
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