Research progress on the impact of dexmedetomidine on acute kidney injury after non-cardiac surgery
Acute kidney injury(AKI)is a common perioperative complication that is strongly associated with an increased risk of death,other postoperative complications,prolonged length of hospitalization stay,and the progression of potential chronic kidney dis-ease.At present,most studies have shown the protective effect of dexmedetomidine(Dex)on renal function.The pathogenesis of AKI af-ter non-cardiac surgery is complex.Dex can reduce the prevalence of AKI through stabilizing renal hemodynamics,diuresis,anti-inflammation and other mechanisms.This article mainly describes the protective mechanism of Dex on renal function,the strate-gies of intravenous Dex infusion,and the related research progress on intravenous Dex infusion,in order to provide clinical reference.
DexmedetomidineAcute kidney injuryNon-cardiac surgery
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NSTL
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