Preoperative sleep disorders affect the sensitivity to sevoflurane and propofol
General anesthesia and natural sleep share similarities in terms of physiological states,primarily involving revers-ible loss of consciousness.Basic researches have confirmed that both induction and recovery of general anesthesia are partially depen-dent on the sleep-wake cycle.But unlike sleep,general anesthesia may extensively suppress cortical activity.This article categories the changes in anesthetic potency of sevoflurane and propofol by primary sleep disorders,such as physiological sleep loss,insomnia,narco-lepsy,sleep apnea syndrome,rhythmic sleep disorders,and sleepwalking.The mechanisms of sleep disorders are complex and not con-sistent across different types of sleep disorders.Based on the possible pathophysiological mechanisms,we briefly analyze the possible reasons for how each type of sleep disorder impact sensitivity to general anesthetic agents.
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