Research advances in programmed intermittent epidural bolus regimens in labor analgesia
Neuraxial labor anesthesia is the safest and most effective way to relieve labor pain.Programmed intermittent epidu-ral bolus(PIEB)is considered a more ideal mode of intrathecal labor analgesia drug delivery than the traditional continuous epidural in-fusion(CEI).However,optimal parameter settings for PIEB have not yet been conclusively determined.This review summarizes and en-capsulates the current domestic and international research advances in PIEB parameters set in the application of intrathecal labor anal-gesia,including bolus volume,inter-bolus interval,infusion rate,and so on.It aims to provide references for better rational and safe clinical application of PIEB and to suggest new perspectives and directions for future researchers.
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