术后认知功能障碍预测方法的研究进展
Research advances on prediction methods of postoperative cognitive dysfunction
李仪 1刘存明1
作者信息
- 1. 南京医科大学第一附属医院麻醉与围术期医学科,南京 210029
- 折叠
摘要
术后认知功能障碍(POCD)是术后常见并发症,表现为与术前相比的认知功能紊乱,不仅导致患者住院时间延长、病死率增加,还可能引发长期的认知衰退.然而,目前尚缺乏有效和可靠的预测指标来识别POCD的发生、发展.因此,确定能有效预测POCD的可靠标志物和方法至关重要.文章综述了近年来在预测POCD方面取得的进展,重点介绍了各类生物标志物和影像学筛查技术,旨在为准确识别高风险人群并进行早期干预提供关键信息,以改善患者预后.
Abstract
Postoperative cognitive dysfunction(POCD)is a common complication following surgery,characterized by a distur-bance in cognitive function compared to the preoperative state.It not only leads to prolonged hospital stays and increases mortality rates but may also trigger long-term cognitive decline.However,currently,there is no effective and reliable predictive indicator for predicting the occurrence and development of POCD.Therefore,it is crucial to find reliable biomarkers and methods that can effectively predict the occurrence of POCD.This review summarizes the recent advances in predicting POCD,with a focus on various biomarkers and ra-diological screening techniques.The aim is to provide key information for the accurate identification of high-risk populations of POCD and early intervention to the patients to improve patient outcomes.
关键词
术后认知功能障碍/预测模型/生物标志物Key words
Postoperative cognitive dysfunction/Predictive indicator/Biomarker引用本文复制引用
出版年
2024
NETL
NSTL
万方数据