Impact of non-alcoholic fatty liver disease on the outcome of patients with acute ischemic stroke
Objective To investigate the impact of non-alcoholic fatty liver disease(NAFLD)on the outcome of patients with acute ischemic stroke(AIS).Methods Patients with AIS visited the Affiliated Jiangning Hospital of Nanjing Medical University between June 2017 and December 2023 were included retrospectively.At 3 months after onset,the modified Rankin Scale was used to evaluate the outcome,with scores of 0-2 defined as good outcome and>2 defined as poor outcome.Multivariate logistic regression analysis was used to determine the impact of NAFLD on the outcome of patients with AIS.Results A total of 143 patients with AIS were enrolled,including 95 males(66.43%),aged 67.79±11.15 years.Ninety six patients(67.13%)had good outcome,and 47(32.87%)had poor outcome.Multivariate logistic regression analysis showed that after adjusting for confounding factors,NAFLD was independently associated with the poor outcome in patients with AIS(odds ratio 2.500,95%confidence interval 1.015-6.161;P=0.046).Conclusion NAFLD is an independent risk factor for poor outcome in patients with AIS.