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脑铁沉积与脑小血管病

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铁代谢是人体的重要生理学过程.当脑铁代谢失衡引起铁超载时,会导致脑铁沉积,使脑细胞发生氧化应激损伤.近年来的研究显示,脑铁沉积与脑小血管病密切相关.文章对脑铁沉积与脑小血管病的最新研究进展进行了综述,以期为脑小血管病的诊治提供新的思路.
Cerebral iron deposition and cerebral small vascular disease
Iron metabolism is an important physiological process in the human body.When the imbalance of brain iron metabolism causes iron overload,it can lead to brain iron deposition,causing oxidative stress damage to brain cells.Recent studies have shown that brain iron deposition is closely associated with cerebral small vessel disease(CSVD).This article reviews the latest research progress on brain iron deposition and CSVD,aiming to provide new ideas for the diagnosis and treatment of CSVD.

Cerebral small vessel diseasesIronIron metabolism disordersWhite matterCerebral hemorrhageCADASILCognition disordersMagnetic resonance imaging

江俊莹、陈雪梅

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南京医科大学附属江宁医院神经内科,南京 211100

脑小血管疾病 铁代谢障碍 白质 脑出血 CADASIL 认知障碍 磁共振成像

2024

国际脑血管病杂志
中华医学会,南方医科大学南方医院,海军总医院

国际脑血管病杂志

CSTPCD
影响因子:0.851
ISSN:1673-4165
年,卷(期):2024.32(5)