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体力活动和锻炼在脑白质高信号中的作用

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脑白质高信号(white matter hyperintensities,WMHs)曾被认为是一种正常的衰老现象.然而,现有证据表明,WMHs是大脑和心血管健康状况不佳的标志,预示着缺血性卒中、认知功能减退、抑郁和死亡风险增高.文章对体力活动和锻炼对WMHs的影响及其机制进行了综述,为更好地预防WMHs提供依据.
Role of physical activity and exercise in white matter hyperintensities
White matter hyperintensities(WMHs)were once thought to be a normal aging phenomenon.However,the available evidences suggest that WMHs are an indicator of poor brain and cardiovascular health,indicating an increased risk of ischemic stroke,cognitive impairment,depression,and death.This article reviews the effects and mechanisms of physical activity and exercise on WMHs,so as to provide a basis for better prevention of WMHs.

Motor activityExerciseResistance trainingCerebral small vessel diseasesWhite matterCognition disorders

李楠、李道静、张爱梅

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济宁医学院临床医学院,济宁 272029

济宁医学院附属医院神经内科,济宁 272029

运动活动 运动(Exercise) 抗阻训练 脑小血管疾病 白质 认知障碍

2024

国际脑血管病杂志
中华医学会,南方医科大学南方医院,海军总医院

国际脑血管病杂志

CSTPCD
影响因子:0.851
ISSN:1673-4165
年,卷(期):2024.32(7)