首页|0~24月龄婴幼儿过敏性疾病流行病学特征及危险因素研究

0~24月龄婴幼儿过敏性疾病流行病学特征及危险因素研究

扫码查看
目的 分析0~24月龄婴幼儿过敏性疾病流行病学特征和危险因素,为后期开展婴幼儿过敏性疾病的干预提供理论依据。方法 于2020年9月-2021年12月,对深圳市龙华区社区健康服务机构开展儿童体检的0~24月龄婴幼儿抚养人进行过敏性疾病问卷调查,收集婴幼儿过敏性疾病相关情况,采用x2检验、t检验、二项Lo-gistic 回归分析模型进行统计分析,探讨婴幼儿过敏性疾病的流行病学特征及危险因素。结果 研究纳入377例婴幼儿,其中男190例,女187例,既往患有过敏性疾病婴幼儿70例,占比18。57%。多因素Logistic分析结果显示,母亲过敏史(OR=3。338,95%CI:1。301~8。563)、家庭装修(OR=4。774,95%CI:1。014~22。479)、婴幼儿服用益生菌(OR=2。051,95%CI:1。061~3。964)、孕期压力(OR=2。073,95%CI:1。132~3。798)是导致婴幼儿过敏性疾病的独立危险因素(P<0。05),而孕期补充益生菌(OR=0。422,95%CI:0。194~0。921)可能是婴幼儿过敏性疾病的保护因素(P<0。05)。结论 深圳市龙华区0~24月龄婴幼儿过敏性疾病患病率较高,建议母亲孕期避免接触装修环境,保持良好的心态,孕期适量服用益生菌,从而减少婴幼儿过敏性疾病的发生。
Study on the Epidemiological Characteristics and Risk Factors of Allergic Diseases in Infants Aged 0~24 Months
Objective In order to provide theoretical basis for the intervention of allergic diseases,by analyzing the related risk factors and epidemiological characteristics of allergic diseases among children aged 0-24 months.Methods From September 2020 to December 2021,the parents of children aged 0-24 months who went to the community health service institutions to carry out physical examination were selected in Longhua district,Shenzhen.A question-naire survey was conducted to collect the data of allergic diseases.Chi-square square,ttest and binomial logistic re-gression were used to analyze the data.The epidemiological characteristics and risk factors of allergic diseases were analyzed.Results A total of 377 children were collected,including 190 males and 187 females.There were 70 infants with diagnosed allergic diseases in the past,accounting for 18.57%.Univariate and multivariate analysis showed that allergic history of mother(OR=3.338,95%CI:1.301-8.563),house decoration(OR=4.774,95%CI:1.014-22.479),probiotics supplementation in infants(OR=2.051,95%CI:1.061~3.964),and high pressure during preg-nancy(OR=2.073,95%CI:1.132-3.798)were the risk factors of allergic diseases in infants(P<0.05).While probiotics supplementation during pregnancy(OR=0.422,95%CI:0.194-0.921)was the protective factor of allergic diseases in infants(P<0.05).Conclusion The prevalence of allergic diseases in infants aged 0-24 months is high in Longhua district of Shenzhen.It is recommended that mothers should avoid exposure to the decoration environment during pregnancy,reduce the occurrence of diseases,maintain a good attitude,and take probiotics appropriately during pregnancy,so as to reduce the occurrence of allergic diseases in infants.

Allergic diseasesInfantsRisk factorsProtective factorsEpidemiological characteristics

何珍、殷道根、曾小辉、范飞翔

展开 >

深圳市龙华区中心医院妇幼保健科,广东 深圳,518110

深圳市龙华区中心医院福城街道区域社康中心,广东 深圳,518110

深圳市龙华区中心医院观澜街道区域社康中心,广东 深圳,518110

深圳市龙华区中心医院皮肤科,广东 深圳,518110

展开 >

过敏性疾病 婴幼儿 危险因素 保护因素 流行病学特征

深圳市龙华区医疗卫生机构科研项目

2020167

2024

中国社会医学杂志
华中科技大学同济医学院

中国社会医学杂志

CSTPCD
影响因子:1.193
ISSN:1673-5625
年,卷(期):2024.41(4)
  • 16