医用一氧化氮制取技术研究进展
Research progress of medical nitric oxide production technology
李倩 1张文露 1王宏 1王妍 1沙洪1
作者信息
- 1. 中国医学科学院 北京协和医学院生物医学工程研究所,天津 300192
- 折叠
摘要
一氧化氮(NO)作为生物体内的信使分子,广泛分布于生物体内各组织中,参与调控细胞的生理活动.吸入低浓度NO可选择性舒张肺血管,其用于临床呼吸急救如肺动脉高压、新生儿低氧性呼吸衰竭和急性呼吸窘迫综合征等相关疾病取得了良好效果.目前除临床上使用化学方法制备NO气体(钢瓶储存)外,放电方式也可产生NO.其中脉冲电弧放电可实现NO随时需要随时制备,解决了常规NO供气源的减压和存储等问题.对NO的临床应用、放电技术以及二氧化氮(NO2)去除方法进行综述.
Abstract
Nitric oxide is a messenger molecule in the body, which is widely distributed in various tissues of living organisms and participates in regulating the physiological activities of cells. Inhalation of low concentrations of NO can selectively relax the pulmonary blood vessels, which can achieve good results and has been applied in clinical respiratory emergency treatment such as pulmonary hypertension, neonatal hypoxic respiratory failure, acute respiratory distress syndrome (ARDS), etc. At present, in addition to the clinical use of chemical methods to produce NO gas (storage in cylinders), NO can also be generated by discharge. Among them, the pulsed arc discharge can realize the preparation of NO at any time and solve the problems of decompression and storage of conventional NO gas supply. In this paper, the clinical application of NO, discharge technology, and removal methods of nitrogen dioxide (NO2) were reviewed.
关键词
一氧化氮/脉冲放电/等离子体/制备/催化还原Key words
Nitric oxide/Pulse discharge/Plasma/Preparation/Catalyticreduction引用本文复制引用
基金项目
天津市自然科学基金(16JCYBJC28900)
国家自然科学基金青年项目(81602800)
出版年
2019
NETL
NSTL
维普
万方数据