HS-SPME-GC/MS法测定生活饮用水中环氧氯丙烷

Determination of epichlorohydrin in drinking water by headspace solid-phase microextraction coupled with gas chromatography/mass spectrometry

李国威 ¹甘平胜 ²李晓晶 ²杨荣 ²刘苗 ²曾涛 ²林静佳¹

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作者信息

1. 广州市白云区疾病预防控制中心,广州 510440
2. 广州市疾病预防控制中心
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摘要

目的建立自动顶空固相微萃取-气相色谱质谱法测定生活饮用水中环氧氯丙烷.方法采用80 μm DVB/Carbon WR/PDMS固相微萃取头,在250 r/min振摇条件下,35℃平衡15 min、顶空萃取15 min,250℃解析5 min,经DB-624色谱柱分离,质谱仪检测,外标法定量.结果环氧氯丙烷在0.2～2.0 μg/L范围内线性良好(r=0.999 2),方法检出限为0.03 μg/L,定量限为0.09 μg/L,相对标准偏差为2.2％～4.6％,加标回收率为95.3％～102.8％.结论本法操作简便,可用于生活饮用水中环氧氯丙烷的测定.

Abstract

Objective To establish a method of automatic headspace solid-phase microextraction(HS-SPME)coupled with gas chromatography/mass spectrometry(GC/MS)for the determination of epichlorohydrin in drinking water.Methods The 80 μm DVB/Carbon WR/PDMS was used as SPME fiber,with the condition of 250 r/min shaking,an equilibration time of 15 minutes at 35 ℃,a headspace extraction time of 15 minutes,and desorption at 250℃ for 5 minutes,and then the compound was separated by a DB-624 chromatographic column,detected by a mass spectrometer,and quantified by the external standard method.Results Epichlorohydrin had good linearity in the range of 0.2-2.0 μg/L(r=0.999 2).This method had a detection limit of 0.03 μg/L,a quantification limit of 0.09 μg/L,a relative standard deviation of 2.2％-4.6％,and a recovery rate of 95.3％-102.8％.Conclusion The method is simple and convenient and can be used for the determination of epichlorohydrin in drinking water.

关键词

环氧氯丙烷/固相微萃取/生活饮用水

Key words

epichlorohydrin/solid-phase microextraction(SPEM)/drinking water

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出版年

2024

环境卫生学杂志

中国疾病预防控制中心

环境卫生学杂志

CSTPCD

影响因子：0.735

ISSN：2095-1906

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