Analysis of disease burden of carbon monoxide poisoning in China,1990-2019
Objective To investigate the disease burden of carbon monoxide(CO)poisoning in China from 1990 to 2019,and to provide a basis for the prevention of CO poisoning.Methods Based on the 2019 Global Burden of Disease database,the incidence,mortality,and disability adjusted life year(DALY)of CO poisoning in China from 1990 to 2019 were analyzed by sex and age and compared with other countries.A Joinpoint regression model was used to analyze the trend of the disease burden of CO poisoning.Results In 2019,the number of new cases of CO poisoning in China was 240 300,with an increase of 13.51%from 211 700 cases in 1990.The standardized incidence rate by the world standard population was 21.82 per 100 000,with an increase of 34.69%from 16.20 per 100 000 in 1990.The number of deaths in 2019 was 15 000,with an increase of 18.11%from 12 700 deaths in 1990.The standardized mortality rate by the world standard population was 0.93 per 100 000,with a decrease of 21.19%from 1.18 per 100 000 in 1990.The DALY decreased by 22.70%from 747 600 person-years in 1990 to 577 900 person-years in 2019,and the DALY rate decreased by 34.95%from 62.91 per 100 000 in 1990 to 40.92 per 100 000 in 2019.From 1990 to 2019,the number of cases,deaths,and DALYs due to CO poisoning in China were all significantly higher in males than in females(t=8.29,15.80,19.91,P＜0.05).In 2019,the standardized incidence rate of CO poisoning in China was low among people aged 40 to 79 years,and increased continually beyond 80-year-olds;the standardized mortality rate was low within 60-year-olds,and the standardized DALY rate was low among 30-to 59-year-olds,both of which rapidly increased beyond 60-year-olds and peaked among 85-to 90-year-olds.From 1990 to 2019,the incidence rate of CO poisoning in China showed an increasing trend,while the mortality rate and DALY rate showed a de-creasing trend,with the annual average percent changes being 1.05%,-0.81%,and-1.42%,respectively.Compared with other countries,China had a lower standardized incidence rate and higher standardized mortality and standardized DALY rates of CO poison-ing from 1990 to 2019.Conclusion From 1990 to 2019,CO poisoning in China showed a fluctuating upward trend in the incidence rate and a fluctuating downward trend in the mortality rate and DALY rate,with a heavy disease burden for males and people≥60 years old(especially≥80 years old),whom should be paid attention to in the future.
carbon monoxide poisoningincidencemortalitydisability adjusted life years
NETL
NSTL
万方数据
