超声波萃取-气相色谱-串联质谱测定PM2.5中18种多氯联苯

Determination of 18 polychlorinated biphenyls in PM2.5 by ultrasonic extraction-gas chromatography-tandem mass spectrometry

苏广宁 ¹王秦 ²朱海燕 ³邓靖 ¹鲁琳 ¹朱盼 ¹钟秀华 ¹梁少婷 ¹罗志彬 ¹龙朝阳 ¹余胜兵¹

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作者信息

1. 广东省疾病预防控制中心卫生化验所,广州 511430
2. 中国疾病预防控制中心环境与健康相关产品安全所
3. 广州市白云区疾病预防控制中心
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摘要

目的建立同时测定大气细颗粒物(PM2.5)中18种多氯联苯化合物的方法.方法采样后的PM2.5滤膜样品中加入氚代多氯联苯替代物,用超声波辅助提取,净化柱净化,气相色谱-串联质谱联用(GC-MS/MS)分析,内标法定量.结果18种多氯联苯的线性范围为1.8～45.0 μg/L,线性关系良好(相关系数＞0.997).方法检出限在0.2～2.0 pg/m3,测定下限在0.8～8.0 pg/m3.样品中多氯联苯低、中、高浓度加标回收率为64.6％～112.0％,相对标准偏差(RSD)在4.02％～10.90％.结论本方法操作简单、灵敏度高、稳定性好,能够满足大气细颗粒物中18种多氯联苯化合物同时检测的需求.

Abstract

Objective To establish a method for simultaneous determination of 18 polychlorinated biphenyl compounds in atmos-pheric fine particulate matter(PM2.5).Methods Surrogates were added to PM2.5 quartz fiber filter samples for ultrasonic-assisted ex-traction,column purification,and quantification by gas chromatography-tandem mass spectrometry with internal standards.Results For the 18 polychlorinated biphenyls,the linear ranges were 1.8-45.0 μg/L,with good linearity(correlation coefficients r＞0.997);the detection limits were 0.2-2.0 pg/m3;the quantitation limits were 0.8-8.0 pg/m3;the recovery rates spiked at low,medium,and high concentrations were 64.6％-112.0％,and the relative standard deviations were 4.02％-10.90％.Conclusion The established method is simple,sensitive,stable,and reliable,which can meet the requirements for simultaneous measurement of 18 polychlorinated biphenyl compounds in atmospheric PM2.5.

关键词

多氯联苯/气相色谱-串联质谱/超声波萃取/细颗粒物

Key words

polychlorinated biphenyl/gas chromatography-tandem mass spectrometry/ultrasonic extraction/fine particulate mat-ter

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出版年

2024

环境卫生学杂志

中国疾病预防控制中心

环境卫生学杂志

CSTPCD

影响因子：0.735

ISSN：2095-1906

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