The impact of regulatory factors on the TGF-β pathway on posterior capsule opacification
Posterior capsule opacification(PCO)is the primary cause of compromised visual acuity in patients following cataract surgery,with an incidence ranging from 30％to 50％in adults and up to 100％in children.The pathogenic mechanism of PCO is complex.The TGF-β pathway influences the epithelial-mesenchymal transition and migration of lens epithelial cells.The expression of certain ribonucleic acids,autophagy or apoptosis can exert influence on PCO formation,thereby leading to the identification of potential therapeutic agents for its prevention.(Int Rev Ophthalmol,2024,48:87-92)
NETL
NSTL
万方数据
