病理性近视的视盘影像标记物
Imaging biomarkers of pathological myopia in the optic disc
卢子兴 1严棽棽 1田蓓1
作者信息
- 1. 首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室,北京 100730
- 折叠
摘要
病理性近视(pathologic myopia,PM)所致的视觉障碍是全球性公共卫生问题,视盘区域形态特征的改变,可预警病理性近视的发生与进展,其中视盘倾斜、视盘及周围视网膜脉络膜萎缩、视盘旁脉络膜空腔等改变与后巩膜葡萄肿的发生存在相关性.PM中视盘病变常与PM相关黄斑病变共存,视盘及周围视网膜脉络膜萎缩区域的发展与扩大可提示近视性黄斑病变的发生与发展.视盘区及周围的血流灌注不足,可能是PM形态与功能改变的原因.及时、准确地识别此类特征性影像标记物有助于PM的防治.(国际眼科纵览,2024,48:93-98)
Abstract
Vision impairment caused by pathologic myopia(PM)is a global public health concern.Changes in the morphological characteristics of the optic disc region can serve as an early warning for the on-set and progression of PM.Alterations such as optic disc tilting,peripapillary atrophy of the retina and cho-roid,and parapapillary choroidal cavitations are associated with the development of posterior staphyloma.Pathologic changes in the optic disc in PM often coexist with PM-related macular degeneration,with the pro-gression and expansion of atrophic areas around the optic disc and the peripapillary choroid indicating the de-velopment of myopic maculopathy.Insufficient blood flow in the optic disc area and its surroundings may be a reason for the morphological and functional changes in PM.Timely and accurate identification of such char-acteristic imaging biomarkers is crucial for the prevention,control,and treatment of PM.(Int Rev Ophthal-mol,2024,48:93-98)
关键词
病理性近视/视盘/视盘周围/影像标记物Key words
pathologic myopia/optic disc/peripapillary/imaging biomarker引用本文复制引用
基金项目
国家自然科学基金(62376167)
国家自然科学基金(62371328)
出版年
2024
NETL
NSTL
万方数据