Imaging biomarkers of pathological myopia in the optic disc
Vision impairment caused by pathologic myopia(PM)is a global public health concern.Changes in the morphological characteristics of the optic disc region can serve as an early warning for the on-set and progression of PM.Alterations such as optic disc tilting,peripapillary atrophy of the retina and cho-roid,and parapapillary choroidal cavitations are associated with the development of posterior staphyloma.Pathologic changes in the optic disc in PM often coexist with PM-related macular degeneration,with the pro-gression and expansion of atrophic areas around the optic disc and the peripapillary choroid indicating the de-velopment of myopic maculopathy.Insufficient blood flow in the optic disc area and its surroundings may be a reason for the morphological and functional changes in PM.Timely and accurate identification of such char-acteristic imaging biomarkers is crucial for the prevention,control,and treatment of PM.(Int Rev Ophthal-mol,2024,48:93-98)
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