Advances in the prevention and treatment of perioperative dry eye disease with cyclosporine
Dry eye disease(DED)is a multifactorial and prevalent disease associated with ocular surface inflammation and impaired lubrication.In recent years,numerous studies have demonstrated that perioperative pharmacological use,surgical trauma,individual factors,and postoperative inflammatory re-sponses are associated with postoperative DED.Cyclosporine selectively regulates T cells,protecting goblet cells and conjunctival epithelial cells while promoting tear secretion.As a result,it effectively alleviates dry eye symptoms in patients,improving the precision of surgeries and patient satisfaction.Currently,cyclospo-rine is widely used in the clinical treatment of perioperative dry eye,achieving favorable outcomes.(Int Rev Ophthalmol,2024,48:103-108)
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