白内障术后黄斑水肿的研究进展
Research advance of peudophakic cystoid macular edema
胡宜卓 1张凤妍1
作者信息
- 1. 郑州大学第一附属医院眼科,郑州 450052
- 折叠
摘要
白内障术后黄斑水肿(pseudophakic cystoid macular edema,PCME)也称Irvine-Gass综合征,是白内障术后无法预测视力下降的常见原因.糖尿病、黄斑前膜、应用前列腺素类似物等为其危险因素.既往认为炎症是其主要的致病因素,近年研究发现很多细胞因子和免疫相关因子可能也参与了 PCME形成.在治疗上除了常规的术后非甾体抗炎药和糖皮质激素点眼之外,还有一些新的防治方法,如术中前房应用去氧肾上腺素/酮咯酸合剂、Tenon囊下/结膜下注射糖皮质激素、玻璃体内注射曲安奈德或地塞米松玻璃体植入剂;术后泪小管地塞米松植入剂及微脉冲激光等.(国际眼科纵览,2024,48:210-216)
Abstract
Pseudophakic cystoid macular edema(PCME),also known as Irvine-Gass syndrome,is the most common cause of unexpected visual loss after cataract surgery.Diabetes mellitus,epiretinal mem-brane,prostaglandin analogues are its risk factors.It's widely accepted that inflammation is the leading pathological mechanism,some cytokines and immune-relatedfactors may contribute to the pathological process.As for the prophylactic and treatment,besides the conventional nonsteroidal anti-inflammatory drug(NSA1D)and steroid,new researches indicate that intraoperative intracameral phenylephrine-ketorolac,subtenon/subconjunctival steroid,dexamethasone implant or triamcinolone acetonide,postoperative intra-canalicular corticosteroids,yellow subthreshold micropulse laser achieve promising outcome.(Int Rev Oph-thalmol,2024,48:210-216)
关键词
白内障/黄斑水肿/Irvine-Gass综合征Key words
cataract/macular edema/Irvine-Gass syndrome引用本文复制引用
出版年
2024
NETL
NSTL
万方数据