The research status of helicobacter pylori vaccines mediated by vectors
Helicobacter pylori infection may result in diseases such as chronic gastritis,peptic ulcer,gastric mucosa-associated lymphoid tissue lymphoma and gastric cancer.It has recently become a highlight to control this bacterium by vaccines.The recombinant proteins including urease,heat shock protein,helicobacter pylori adhesin A,catalase,cytotoxin associated protein A,vacuolating cytotoxin A and neutrophil-activating protein are some of the effective candidate molecules of vaccines.This paper reviews the research status of these vaccines of helicobacter pylori mediated by bacteria such as salmonella typhimurium,bifidobacterium bifidum,mycobacteria smegmatis,bacillus subtilis,lactococcus lactis,agrobacterium tumefaciens,measles virus,poliovirus,baculovirus and adenovirus.
NETL
NSTL
万方数据
维普
